Review Regarding the Impact of Vitamin D Deficiency on the Function of Immune System

Document Type : Review

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Abstract
The long-held knowledge regarding vitamin D is that it could affect both homeostasis of calcium and bone metabolism. It is a vital immune regulator which has impact on the immune systems' innate and adaptive components as it is based on the mounting data. Research has shown that vitamin D deficiency is linked to several of immune-mediated illnesses, infection, vulnerability, and cancer. The objective of this article is to highlight the importance of this vitamin and clarifying the relationship between the immune system and it in general in addition to the innate and acquired immunity in particular.

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Volume 12, Issue 1
Winter 2026
Pages 144-158

  • Receive Date 02 October 2025
  • Revise Date 16 November 2025
  • Accept Date 21 November 2025
  • First Publish Date 01 January 2026
  • Publish Date 01 January 2026