Al-Kunooze Scientific Journal

Study the Effect of Different Laurel Plant (Laurus Nobilis) Extracts at Different Periods on Some Biochemical Markers in Experimental Rats Induced by Diabetes

Document Type : Original Article

Author

Aser Ihsan Abdullah, Saba Zeki Al-Abachi
Abstract
This study included isolating and extracting the active compounds from the leaves of the Laurus Nobilis plant and studying their effect on alloxan-induced diabetic rats. Oils, flavonoids, and tannins were extracted in the extraction device in successive stages using several solvents. The study used (48) white adult male rats, whose ages ranged between (12-14 weeks) and their weights (135.5±7.9 gm) were randomly divided into (6) rats per group, to perform experiments. Eexperiments showed the effect of oily, flavonoid, and tannin extracts of the plant at a dose (250 mg/kg of B.W.) on some biochemical changes associated with diabetes such as glucose, total cholesterol, triglycerides, and high-density lipoprotein cholesterol as well as their effect on the activity of liver enzymes (alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase) in serum of healthy, adult and newly introduced diabetic rats treated with the three extracts orally for 15 and 30 days possess the natural products extracted from plant and represented by oils, flavonoids and tannins.

Keywords

Alloxan
Diabetic
Laurus Nobilis
Liver enzymes
Triglyceride

  • Receive Date 15 November 2025
  • First Publish Date 15 November 2025
  • Publish Date 01 June 2024

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